pdf Detection of Some Common Genes in Different Genetic Model Organisms

Mohammad Ibrahim Khalil and Noor Myasar Sadeq

Abstract

Four genetic model organisms; Zebrafish, Arabidopsis thalina, Neurospora crassa and Homo sapiens used to detection and comparison of some important homologous genes; TP53, WC-1, Clock and TNF. PCR primers for each gene were designed and amplify against the four organisms. Three primes to amplify of TP53 and one primer for the WC-1 and Clock gene to all organisms and two primers for the TNF. The results showed there are a strong relation and homologous among the genes amplified by the primers, for these genes all organisms have a different genes name but have similar function in effective, the result also showed the possibility to use may organisms as a model to study some important genes and simulation the human genes for drug designed and genetics therapy.