pdf Determination of Toxoplasma Gondii Genotypes from Mice Inoculation as an Iraqi Strains

Dr. Safa Ibrahim Jaber

Abstract

In this study, (50) mice were inoculated by Toxoplasma gondii Tachyzoite taken from Amniotic Fluids and partially extracted placental in Alzahraa Hospital/ Diyala Province, during the period from February  to October 2024. The results showed that The prevalence rate of Toxoplasmosis inoculated in mice according to the age 2 weeks was 14 (28.0%), 3 weeks was 17 (34.0%), and the prevalence rate 4 weeks, 5 weeks and 6 weeks was 4 (8.0%) respectively. Also, the distribution of Toxoplasmosis according to sex showed that prevalence rate in male was 30 (60%) and in female 20 (40%). The mean ±SD of  IgM was (0.97±0.22) and mean ±SD of  IgG was (1.30±0.24). The Mean±SD of IgM concentration in male was (0.89±0.29) and in female was (1.09±0.29) with significant variation (P=0.019). Also, the Mean ±SD of IgG concentration was (1.40±0.31) in male and the Mean ±SD of IgG concentration was    (1.20±0.32) in female with significant variation (P=0.024). The mean of IgM in the age 2 weeks was 14 (1.00±0.25 B), and in the age 3 weeks was 17 (0.89±0.22 B), and in the age 4 weeks was 9 (0.94±0.18 B), in the age 5 weeks was 6(1.01±0.15 AB), in the age (6) weeks was (1.21±0.06 A), with significant variation (P=0.043).  A clonal (Type II) was identified in 48 (93.3%), and type I was identified in 9 (15.25%), while type III was identified in 2 (3.38%), and these findings are considered entero-zoonotic parasite and this case recorded in Iraq for the first time.