A Comparative Biochemical Study of Oxidative Stress and Lipid Profiles in Patients with Acute Myocardial Infarction
DOI:
https://doi.org/10.65204/DJMS-ACBS-OSKeywords:
Acute Myocardial Infarction, Diabetes Mellitus, Ceruloplasmin, Malondialdehyde, Reactive Oxygen Species, Lipid ProfilesAbstract
This study aimed to evaluate oxidative stress and lipid profiles in diabetic and non-diabetic acute myocardial infarction (AMI) patients. A cross-sectional analysis of clinical and laboratory data was conducted at Al-Hussein Educational Hospital in Al-Muthanna, Iraq, in collaboration with the College of Science at Al-Muthanna University. Data were collected for 84 subjects divided into three groups: non-diabetic AMI (GMI), diabetic AMI (GMI-DM), and diabetic (GDM). Biochemical parameters measured included malondialdehyde (MDA), ceruloplasmin (Cp), total cholesterol (Cho), triglycerides (TG), low-density lipoprotein (LDL), high-density lipoprotein (HDL), and very low-density lipoprotein (VLDL), along with the patients' age and gender. MI, MIDM, and DM groups exhibited high levels of MDA, Cho, TG, LDL, and VLDL, with low levels of Cp and HDL compared to healthy controls. The study demonstrated increased oxidative stress and dyslipidemia in MI patients compared to controls, regardless of diabetes status.